Pyometra in Cats

Pyometra, Pyo

Image placeholder

Updated on September 26, 2024
SUMMARY OF CONTENT
Pyometra in cats is a secondary bacterial uterine infection caused by a hormonal imbalance.
SEVERITY:
Severe, needs immediate veterinary treatment

  • Diagnosis Icon
    A rare condition, “Stump Pyometra”, can happen in spayed animals if an ovarian remnant is left behind.
  • Time to Cure
    Resolves within days to weeks with proper medical treatment and/or surgery but can be a fatal condition
  • Treatment Icon
    Treatable by a veterinarian
  • Prevention Icon
    Spaying female cats at an early age will prevent pyometra later in life
  • Spread Icon
    Transmission is not possible between animals, or from animals to people
  • Lab Icon
    Diagnosis requires physical exam, lab tests, x-rays, and/or ultrasound.

VERY COMMON IN
Pyometra is mainly a disease of middle-aged female cats that have not been spayed, but can occur in any intact, female cat that has gone through a heat cycle.

Symptoms & Signs

The most common sign of pyometra is a white, yellow or blood-tinged discharge from the vulva. The cat will lick at her vaginal area while the cervix is still open and the uterus is discharging a white fluid. The abdomen may appear distended and the cat may have a decreased appetite, vomiting or lethargy. Some cats will have a fever and some may become dehydrated. Many cats do not show any obvious signs of apparent illness beyond discharge, which they may easily hide if they are routinely grooming themselves, until late- stages of the disease. If blood work is done, it will show an elevated white blood cell count and possibly mild anemia.

Diagnosis

A physical exam of the cat followed by blood work and evaluation of any vaginal discharge may diagnose pyometra. An abdominal x-ray or ultrasound will be performed to confirm the diagnosis.

Causation

In the past, it was thought pyometra was simply a uterine infection. Today, we know that it is a hormonal abnormality, and a secondary bacterial infection may or may not be present. Pyometra follows a heat cycle in which fertilization did not occur. Typically, within one to two months after the cycle, the female starts showing signs of the disease. The two main hormones produced by the ovaries are estrogen and progesterone. An excessive quantity of progesterone, changes in the uterine wall leading to cysts forming, and introduction of bacteria into the uterus causes pyometra. Large quantities of fluids are produced and released into the interior of the uterus as the cysts grow. Bacteria commonly colonize the uterus by entering through the cervix. This produces an even greater response by the body, as it showers additional fluid and white blood cells into the affected organ. This fluid, along with a thickening of the walls of the uterus, brings about a dramatic increase in the overall size of this organ. As the disease  progresses, fluid moves from the uterus to the vagina and then spills out onto the vulva causing the animal to lick this area in an attempt to keep herself clean. In some cases of pyometra, the cervix closes. This effectively traps all of the fluid within the uterus. Still, the body continues to transfer more fluid and white blood cells into the organ, causing even further dilation and growth. The uterus can rupture, spilling its contents into the abdominal cavity. This would be a serious  and potentially fatal medical condition. The body will attempt to eliminate the problem by carrying the wastes and excess fluid through the bloodstream to the kidneys. The normal toxins that should be excreted from the body build up and overwhelm the kidneys, and the animal goes into uremic poisoning. If left untreated, she will die from kidney failure.

Treatments

icon SUPPORTIVE CARE
Since toxicity may develop very quickly in cats with pyometra, it needs to be treated promptly. The cat may need intravenous fluids to treat shock and stabilize her condition. Monitor the incision site if surgery was performed.
icon MEDICATIONS
In some females who must remain intact, prostaglandin and antibiotic therapy may be tried instead of surgery. The prostaglandin causes the uterus to contract and expel the fluid. In mild cases, when the cervix is still open and the fluid is draining, the success rate can be good. Prostaglandins, however, can have side effects including panting, vomiting and diarrhea. In some queens whose condition is unstable, the side effects are too severe and the treatment needs to be discontinued. Antibiotics will also be prescribed to treat infection.
icon DEVICES
None
icon SURGERY
In most cases, the preferred treatment is a complete ovariohysterectomy (spay). This removes the ovaries, oviducts, uterus and all associated blood vessels. These animals can be a surgical challenge because of their poor overall condition. Medicate as directed by your veterinarian. Pyometra is a life-threatening condition and cats with this suspected condition should be seen by your veterinarian immediately. Intravenous fluids are often recommended to reduce the chance of dehydration, especially for cats that are unwell or not drinking well on their own.
icon SPECIALISTS
A general practice veterinarian typically manages pyometra in cats, however a veterinary specialist in surgery or critical care may be needed in severe cases.

Cost Of Treatment

While veterinary costs vary for a number of reasons, surgery to treat pyometra may cost between $1500 and $3000.

Recovery

Recovery from pyometra usually occurs within days to weeks depending on the type of treatment and response. In cats that are treated with and respond to medical therapy, the cat typically recovers within a week after medications are started. There is, however, a risk of recurrence after each heat cycle. With surgical correction, expected recovery time is generally expected within two weeks with no risk of recurrence as long as no ovarian remnant remains.

Monitoring

When medical therapy is used to treat pyometra, the cat needs to be monitored for recurrence by watching for common signs of pyometra, including decreased appetite, lethargy, vaginal discharge/licking, vomiting and fever. If surgery is performed, a follow-up examination will be scheduled 10-14 days after surgery for suture removal. If surgery is performed, the cat should be kept to a confined area with reduced activity and fit with a surgical cone or surgical recovery suit to help prevent manipulation of the sutures. Thoroughly inspect the cone or recovery suit often to ensure your pet does not have access to the surgical site.

Prevention

The best prevention of pyometra is to have all female cats spayed at or before six months of age. Pyometra is a fairly common and serious problem, but it is just one of many compelling reasons to have your female pet spayed at an early age.

image

Have A Vet Question?

Book an appointment with the pros – our expert vets are here to help.

Files Under:

Disclaimer

The information contained on this page is for educational purposes only. This medication should only be given under the advice of a veterinarian who has examined your pet under the laws applicable to your state of residence.