Acetaminophen is a pain reliever and fever reducer that is occasionally used in dogs and small mammals. It is not labeled in the USA for use in animals, therefore any such use is off-label. It can be used in combination products containing codeine, hydrocodone, or tramadol. It should never be used in cats, ferrets, hedgehogs, or sugar gliders.
Acetaminophen can be used in veterinary medicine to control pain and reduce fever in dogs and small mammals.
Acetaminophen relieves pain and reduces fever by inhibiting cyclooxygenase (COX-3; Cox-1-v1).
Acetaminophen tablets and liquid suspensions should be stored in a childproof container at room temperature in a location out of reach of animals.
It is best to give the medication at the same time every day without skipping doses. If you miss a dose, give it as soon as possible. If it is almost time for the next dose, skip the one you missed and go back to the normal schedule. Do not give 2 doses at the same time.
Vomiting, diarrhea, lethargy, facial and paw swelling, labored breathing, gray colored gums, and jaundice may be seen in cases of overdose. If you think your pet has had an overdose seek veterinarian care immediately.
Consult your veterinarian before using acetaminophen with any other medications, even vitamins and supplements. Barbiturates, non-steroidal anti-inflammatories, corticosteroids, diazepam, doxorubicin, fenbendazole, isoniazid, phenothiazines, propylene glycol, and anti-coagulants may interact with acetaminophen.
Acetaminophen must be avoided in cats, ferrets, hedgehogs, and sugar gliders at any dose due to significant toxicity. Acetaminophen should be given to dogs and some small mammals only under close veterinary supervision due to the potential for toxicity.
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