Phenobarbital is primarily used in veterinary medicine to control epilepsy and seizures. Also used as a sedative and for controlling excessive feline vocalization.
Phenobarbital works by decreasing the abnormal electrical activity in the brain that happens during a seizure.
Store in a tight, light resistant, childproof container at room temperature.
It is best to give the medication at the same time every day without skipping doses. If you miss a dose, give it as soon as possible. If it is almost time for the next dose, skip the one you missed and go back to the normal schedule. Do not give 2 doses at the same time.
May see staggering, sedation, loss of appetite, vomiting, depression, jaundice (yellow gums, skin, eyes), decreased breathing and heart rate, coma, and death. If you think your pet has had an overdose seek veterinary care immediately.
Consult your veterinarian before using any other medications with phenobarbital, even vitamins and supplements. Interactions may occur with acetaminophen, NSAIDs (e.g., aspirin, carprofen, firocoxib, etodolac, deracoxib, and meloxicam), MAO inhibitors (amitraz, selegiline), phenytoin, and rifampin. Antihistamines, chloramphenicol, felbamate, opiates, phenothyazines, urinary acidifiers, and valproic acid may increase the effects of phenobarbital. Phenobarbital may decrease the effect of oral anticoagulants (blood thinners, warfarin), beta blockers (propranolol), chloramphenicol, corticosteroids (e.g., prednisone, dexamethasone), doxycycline, griseofulvin,itraconasole, levothyroxine, metronidazole, praziquantel, theophylline, tricycline antidepressants, urinary alkalinzers, zonisamide.
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