Spironolactone is an aldosterone antagonist that is used as a potassium sparing diuretic in dogs or cats that develop low potassium on other diuretic medications. It can be used as adjunctive treatment in congestive heart failure in dogs and cats, and is used as an adjunctive treatment for hypertension in cats. Use in animals is extra-label in the United States; veterinary labeled products available in other countries. [Buy Spironolactone now on Petco.](https://www.petco.com/shop/en/petcostore/brand/spironolactone) A prescription from your veterinarian is needed to purchase.
Spironolactone may be used as an adjunctive diuretic in the treatment of congestive heart failure, but its use is controversial in dogs. It can also be effective as an adjunctive treatment for hypertension (high blood pressure) in cats.
Spironolactone blocks aldosterone (a hormone) in the distal tubules of the kidneys, resulting in increased excretion of sodium, chloride and water.
Keep in a childproof, light resistant container at room temperature away from children and pets.
If you miss a dose, give the next dose as soon as possible. If it is almost time for the next scheduled dose, skip the missed dose, and give itat the regularly scheduled time. Do not give two doses at once.
If you suspect that your pet has ingested an overdose, contact animal poison control. Information about overdoses of spironolactone is unavailable.
Always consult your veterinarian before using spironolactone with any other medication, including vitamins and supplements. Increased potassium is possible if spironolactone is given with potassium supplements or other potassium sparing diuretics. Aspirin and other salicylates, digoxin and mitotane may interact with spironolactone.
Patient with impaired liver or kidney function. Avoid use in pregnant or lactating animals. Do not administer in conjunction with certain drugs.
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