Dimenhydrinate

Updated on September 10, 2024
Dimenhydrinate is an anti-histamine/anti-emetic used to prevent motion sickness in dogs.
Dimenhydrinate

Summary

Used For:

Prevention of motion sickness in dogs

Brands:

Dramamine

Species:

Primarily dogs

Other names:

Draminate, Gravol, Triptone, TravTabs

Drug type:

Antihistamine

Prescription required:

No

Pregnancy and lactation:

Use in pregnant or lactating animals has not been evaluated.

Side effects:

Sedation, dry mouth and inability to fully empty the bladder
 

General description

Dimenhydrinate is an anti-histamine/anti-emetic used to prevent motion sickness in dogs. Can be used in cats, but better choices are available. Veterinary use is extra-label.

Uses

Used to decrease motion sickness in dogs

How it works

Dimenhydrinate blocks the stimulation of the vestibular system in the brain which helps to reduce the clinical signs associated with motion sickness.

Dosage

**Dogs and Cats**: 4 – 8 milligrams per kilogram of body weight by mouth every 8 hours.

Forms

Oral Tablets: 50 mg (regular & chewable)

Storage information & handling

Tablets: stored at room temperature protected from moisture and light.

What results can I expect?

Resolution of vomiting and motion sickness.

Missed Dosage

If a dose is missed, continue with the next dosage at the scheduled time.

Overdose / acute toxicity

May see excitement or seizures, lethargy, or coma, respiratory depression, or death with overdose.

Side effects

May include: * Sedation * Dry mouth * Urinary retention * Decreased appetite * Vomiting * Diarrhea

Contraindications

Avoid use in pets with: * Known hypersensitivity * Angle closure glaucoma * Prostatic hypertrophy * Stomach or intestinal obstruction, * Urinary obstruction * COPD * Hyperthyroidism * Seizures * High blood pressure

Drug interactions

Consult your veterinarian before using dimenhydrinate with any other medications, even vitamins and supplements. The following drugs may interact with dimenhydrinate: * Anticholinergic drugs (including tricyclic antidepressants) * CNS depressant drugs

Precaution

Use with caution in working animals, as sedation may interfere with job performance.

Sources

Plumb’s Veterinary Drug Handbook

VIN Veterinary Drug Handbook

Manufacturer information: 

  • Prestige Consumer Healthcare - Dramamine
  • Church & Dwight - Gravol (Canada)

Disclaimer
The information contained on this page is for educational purposes only. This medication should only be given under the advice of a veterinarian who has examined your pet under the laws applicable to your state of residence.

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