Gentamicin is an antibiotic with broad spectrum of activity against gram-negative, aerobic bacteria. Gentamicin is used frequently in veterinary medicine to treat infections that are resistant to other antibiotics. Aminoglycosides are usually administered in a hospital setting as it is given via injection or infusion. Use with care as bacterial resistance to Gentamicin is developing. While many medications are often administered for ‘off-label’ or 'extra-label' use in veterinary medicine, it is important to know that off- or extra- label use of a medication can only be done by a veterinarian when there are no other more appropriate medications for a particular pet's circumstances. Your veterinarian must also know all vitamins, supplements, medications etc. your pet is taking to help avoid complications. You must also be sure to follow all instructions provided by your vet carefully and consult your veterinarian with any questions or concerns if they arise.
Infections caused by gram-negative bacteria
Gentamicin works by inhibiting bacterial replication by preventing the bacteria from making proteins. It works best at killing staphylococcal and gram-negative bacteria in the enterobacteriaceae family.
Injectable gentamicin can be stored at room temperature.
If a dose is missed, continue with the next dosage at the scheduled time.
Early signs of toxicity include loss of hearing and balance or vomiting. May see symptoms of kidney disease including increased or decreased drinking, lack of appetite, vomiting, depression, coma and death.
Do not use with diuretics as it increases the risk of kidney damage. Do not use in combination with other aminoglycosides. Do not use with other products that may cause hearing loss, vestibular disease or kidney disease. Do not use with general anesthetics.
Gentamicin is not safe to use during pregnancy and lactation.
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